Nonclinical · v1
Peptide research,
replayable.
Twelve agents. Hashed before. Revealed after.
The Loop5 stages
- 01Commit
- 02Ingest
- 03Reason
- 04Critique
- 05Reveal
commit · reveal · verify
12
Agents
10
Stages
A — X
Grades
sha-256
Commit
Five stages.
One hash.
Protocol
- 01Commit
- 02Ingest
- 03Reason
- 04Critique
- 05Reveal
Twelve specialists.
Architecture
- 01
Literature Miner
upstream · PubMed - 02
Sequence & Structure
upstream · UniProt · AlphaFold - 03
Target & Pathway
upstream · OpenTargets - 04
Variant Linker
upstream · ChEMBL - 05
ADMET Developability
upstream · Heuristic - 06
Novelty Scout
reasoning · Whitespace - 07
Patent Competitive
reasoning · Lens.org - 08
Thesis Generator
reasoning · kie · gpt-5-4 - 09
Evidence Grader
reasoning · A — X rubric - 10
Red Team
reasoning · 3 personas - 11
Synthesizer
output · Cross-pool - 12
Dossier Assembler
output · Markdown
The output is a single dossier.
Output
dossier · schema
markdown## Question <the original mission query, verbatim> ## Cross-pool consensus - Literature PubMed citations - Sequence UniProt + AlphaFold - Target/pathway OpenTargets - Chemistry ChEMBL ligand prior ## Open questions ## Risks ## Recommended next steps
- Cited.Every claim has a real PMID.
- Hedged.No human-use claim, ever.
- Hashed.Replayable end-to-end.
Built so you don’t have to trust us.
Principles
- 01
Falsifiability is a first-class artifact.
- 02
Evidence is graded, not gestured at.
- 03
The red team can actually block.
- 04
A clean falsification is a successful run.